Stem Cells and Skin Archives
Researchers Devise New Technique for Creating Human Stem Cells
Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem cells. The fusion causes the adult cells to undergo genetic reprogramming, which results in cells that have the developmental characteristics of human embryonic stem cells. The new technique may permit scientists to derive new human embryonic stem cell lines without the need to use human embryos.
This approach could become an alternative to somatic cell nuclear transfer (SCNT), a method that is currently used to produce human stem cells. SCNT involves transferring the nuclei of adult cells, called somatic cells, into oocytes in which scientists have removed the nuclei.
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Posted on August 23, 2005 09:21 AM | Comments (0)
More on Skin Cells "Made Into" Embryonic Stem Cells
Following up on the embryonic stem cells created from skin cells ... this news is flying wildly all over the internet ... with posts coming in from many sources .. will try to post a few of them here ...
Many of the mainstream journals are reporting how Harvard researchers have for the first time have turned ordinary skin cells into what appear to be embryonic stem cells. The biggest piece of this that makes people sit up is, this is all done without using human eggs or making new human embryos in the process .. essentially what has always been required in the past.
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Posted on August 23, 2005 09:03 AM | Comments (0)
Fetal Skin Cells Assist In Healing Burn Victims
Nature is reporting on how applying of a small number of fetal cells to burn patients can spead recovery from their injuries. Futhermore, this latest procedure reportedly provides a faster and more complete recovery than the traditional skin grafts.
Current methods of treating deep second- and third-degree burns with skin grafts involves a two-step surgical procedure where a patch of skin is removed from one area of the body and transplanted to burned area. Though an effective treatment, the patient is often left with severe scaring and may take months to heal.
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Posted on August 19, 2005 05:28 PM | Comments (0)
Howard Hughes Medical Institute Study Shows How Skin Forms Deep Layers
Howard Hughes Medical Institute researchers have new evidence that pushes aside old theories about how skin is able to create layers of different cell types while simultaneously forming a continuously self-renewing, protective barrier.
The discovery helps to explain how skin becomes “stratified” into different layers and may yield new insights into the basic processes by which stem cells can both self-replicate to produce more stem cells and also mature and differentiate to form a tissue.
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Posted on August 17, 2005 03:33 PM | Comments (0)
Harvard Researcher Develops New Method Similar to Dedifferentiation
Technically speaking, I don't think this is full blown dedifferentiation, as we know thats a method of causing an adult cell to revert back to a stem cell. However, this is close on the heels of that kind of research.
Nature is reporting on new a research project being run by Kevin Eggan of the Harvard Stem Cell Institute. Recently he told an international scientific meeting that his lab has fused a human embryonic stem cell to an adult skin cell. Eggan further showed that the embryonic stem cell effectively "reprogrammed" the skin cell's nucleus, which then caused the skin cell to start behaving like an embryonic stem cell.
Eggan's research gives rise to the possibility that researchers may be able one day to develop human embryonic stem cell lines genetically matched to individual patients without first having to create an embryo clone of the patient. The theory is that researchers could reprogramme a patient's skin cells to behave like stem cells.
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Posted on June 28, 2005 01:22 PM | Comments (0)
Wake Forest Researchers Grow Stem Cells From Skin
Researchers at the Wake Forest University School of Medicine are announcing that they have successfully isolated stem cells from human skin. Further, they have grown them in the lab and then finally caused them to differentiate into fat, muscle and bone cells.
This latest study, is one of the first studies to show that a single adult stem cell can actually differentiate into multiple tissue types.
"These cells should provide a valuable resource for tissue repair and for organs as well," said Anthony Atala, M.D., director of the Wake Forest Institute for Regenerative Medicine and senior researcher on the project. "Because these cells are taken from a patient’s own skin, there would not be problems with organ or tissue rejection."
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Posted on June 23, 2005 01:19 PM | Comments (0)
Cloned Embryos Created to Match Stem Cells, Patients
South Korean scientists have announced a highly efficient way to clone human cells. This latest discovery could alter the scientific and political debate over the procedure.
Effectively they have created 11 new lines of cloned human embryonic stem cells. For the first time, this includes two that are genetically matched to patients with a disease. The two disease-carrying cell lines were cloned from patients with juvenile diabetes and an inherited blood disorder.
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Posted on May 20, 2005 01:13 PM | Comments (0)
Cloning To Develop Stem Cells In An Effort To Cure Blood Diseases
In the fight to turn back the fatal blood diseases like leukemia, the most powerful tool thusfar has been the bone-marrow transplant. However, many patients are unable to find a donor who is a close-enough match to limit the risk of rejection.
Even in the instance when there is a good match, the overall treatment procedure is still quite risky. The Children's Hospital in Boston is considered one of the best program is considered one of the world's bes. Nevertheless, 8 percent of its transplant patients die within approximately one year, as indicated by last year's statistics....
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Posted on May 17, 2005 02:07 PM | Comments (0)
OffTopic .. Only a Little .. Inkjet Nozzles To Spray Live Human Cells Onto Patients?
Scientists at the University of Manchester in England working to develop a technique in which inkjet nozzles spray live human cells onto a patient.
This methodology could speed up a patient's healing process because doctors could "spray" on replacement tissue that would grow to the size and shape required. These new "seed cells" could also be grown from a previously harvested sample from the patient, thereby reducing the chances of donor rejection.... Sounds like a perfect combination to some of the stem cell therapy options we keep reading about ....
...Posted on April 7, 2005 12:47 AM | Comments (0)
Chicago: Stem Cell Research May Provide Better Looking Cosmetic Surgery
Stem cell researchers have shown that cosmetic surgery, such as wrinkle removal and breast augmentation, may actually beimproved with natural implants that keep their original size and shape better rather than the current synthetic implants.
In the near future cosmetic surgery might be performed with stem-cell generated natural tissues instead of synthetic implants.
As is well known, saline and silicone implants for breast augmentation can rupture, leak, and interfere with breast cancer detection on mammograms.
Stem cell generated natural tissue implants should avoid these problems...
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Posted on February 17, 2005 07:44 PM | Comments (0)
California: New Blood Revives Old Muscles
Researchers out at Stanford University have found that an infusion of young blood into older "patients" has some pretty significant benefits.
The scientists have linked the blood supply of young mice to old mice, and what they have found will impact stem-cell research as well as the scientific study of aging: The young blood activated stem cells in the old muscles that allowed them to recover from injury and deterioration.
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Posted on February 17, 2005 11:48 AM | Comments (0)
United Kingdom: Sheffield University hoping To Profit From Stem Cell Venture
A company controlled by the University of Sheffield is seeking to raise £10m to fund the commercialisation of its academics' discoveries, ranging from stem-cell science to repairing severely burned skin.
Biofusion is 70% owned by the university and has stakes in more than eight companies that have been spun out of the institution. It plans to float on the Alternative Investment Market, with an estimated value of £30m, if it can persuade investors to back its venture. After the flotation the university's stake would be worth about £15m.
It is making a loss at present but will seek to make money by floating off its spin-outs. The two university ventures that are the nearest to this point are about 18 months away from flotation. Molecular Skincare is working on a cream to help people with atopic eczema and contact dermatitis, and it may be possible to sell it without the need for expensive clinical trials....
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Posted on February 12, 2005 01:49 AM | Comments (0)
Dermatologists Find Solutions in Stem Cells
A new process to slowly freeze stem cells will increase the viability of fat cells used as fillers - which can lead to permanent fat transfers to areas of the body including the breast. This new technique will prove especially beneficial for patients of lumpectomies and biopsies who may be left with an indent in breast tissue after their procedures... Read On
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Posted on December 13, 2004 09:27 AM