Stem Cells and Cancer Archives
Molecular Imaging Used To Track Stem Cells In Tumors
Researchers at Society of Nuclear Medicine's 55th Annual Meeting, June 14-18, say that new therapies offer promise for patients
Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms, according to researchers at SNM's 55th Annual Meeting. This ability could lead to major advances in the use of stem cell therapies to treat cancer.
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Posted on June 16, 2008 06:15 PM | Comments (0)
Dismissing Cancer Stem Cells
Scientists have found the Achilles' heel of cells that jump start tumor growth.
According to a new study, these "cancer stem cells" reside in blood vessels. The researchers say that disrupting these vessels may prove a far more effective cancer therapy than targeting other regions of a tumor.
Cancer stem cells are the ultimate source of the tumor, consistently supplying it with new cells.
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Posted on January 22, 2007 11:20 PM | Comments (0)
Stem Cell Marker Identified On Head And Neck Tumor Cells
In a study at the University of Michigan Medical School researchers have found a marker on head and neck tumor cells that indicates which cells are capable of fueling the cancer’s growth.
By identifying the stem cells, researchers can then develop drugs to target and kill these cells.
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Posted on January 19, 2007 05:14 PM | Comments (0)
What is Glioblastoma?
Glioblastoma is the most malignant form of brain tumor and has a very poor prognosis.
A glioma is a type of primary central nervous system (CNS) tumor that arises from glial cells. The most common site of involvement of a glioma is the brain, but they can also affect the spinal cord, or any other part of the CNS, such as the optic nerves.
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Posted on January 19, 2007 07:11 AM | Comments (0)
At UKY Researchers Map Gene that Regulates Adult Stem Cell Growth
The researchers at the University of Kentucky have genetically mapped a stem cell gene and its protein product, Latexin.
Gary Van Zant, Ph.D., and a research team published their findings in Nature Genetics, an international scientific journal.
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Posted on January 16, 2007 03:07 AM | Comments (0)
Targeting Cancer Related Stem Cells And Avoiding Healthy Cells
Go out of town for a bit, and the news keeps on rolling. I will try and do some catchup as I go ..
Howard Hughes Medical Institute is looking into the unique properties of stem cells that both cause normal blood cells to develop, and that also may cause leukemia.
Stem cell and cancer researchers are now saying that there is in fact a big dfferent between normal stem cells and the stem cells that develop into leukemia. Experiments using mice are showing that the stem cells that develop into leukemia can be killed by rapamycin, a drug has received Food and Drug Administration (FDA) approval.
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Posted on April 6, 2006 12:58 PM | Comments (0)
Stem Cells Differentiation Process Involved with Leukemia
Researchers have recently discovered what manages the balance between blood stem cells and mature blood cells within the body. This bodily process is often what is seen in leukemia patients.
News coming from an article published in the journal Cancer Cell, will hopefully lead researchers to a better understanding of the behavior of leukemic cells. Additionally, this may provide applications for patients recovering from radiation therapy, bone marrow transplants, and chemotherapy.
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Posted on March 23, 2006 01:53 PM | Comments (0)
Stem Cells Found In The Lung
Researchers at MIT's Center for Cancer Research have discovered stem cells in the lung.
This is thusfar, the first time anyone has found stem cells in the lung that we know of. The MIT team claims that these cells could be the stem cells that cause lung cancer.
"We think those cells are the ones that first proliferate after a [cancer] gene gets activated," says Carla Bender Kim, a postdoctoral fellow at the center and lead author of the study, which was published in the journal Cell.
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Posted on March 14, 2006 03:27 PM | Comments (0)
Stem Cell Research Comes to Scripps Research Institute
Scripps Research Institute is to start a new study that focuses on embryonic stem cells as a participant in a consortium of three stem cell California bioscience institutes and a university. The goal of the joint venture is to build their California's first center to specifically target stem cell research and cancer.
Scripps, joins with the Burnham Institute for Medical Research and the Salk Institute. Their goal is apply for state funds that would then allow the new center to be developed on the University of California San Diego campus.
This is part of the funds that are being made available through California's Proposition 71
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Posted on March 12, 2006 03:00 PM | Comments (0)
Study Researching Stem Cell Treatment for Chrohn's Disease
A new clinical study at Northwestern University of Chicago, Illinois suggest that stem cell transplant seemingly may stop the progression of Crohn’s disease.
The researchers, from Northwest University's (NU) Feinberg School of Medicine are performing the technique to combat other autoimmune disorders for which there are no effective therapies.
The study's findings were presented at the annual Blood and Marrow Tandem Meetings (BMT).
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Posted on March 8, 2006 05:02 PM | Comments (0)
Prostate Tissue Grown From Stem Cells
Scientists in Australia, are reporting that they grown a human prostate gland from embryonic stem cells.
Monash Institute of Medical Research scientists are saying that it took them 12 weeks to develop human embryonic stem cells into human prostate tissue.
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Posted on February 26, 2006 07:44 PM | Comments (0)
Stem Cells Root Cause Of All Cancers?
Well, if there was ever a reason to write that article on what the advantage of stem cell research is .. here is a classic example.
Researcher Robert Weinberg, a cancer geneticist at the Whitehead Institute in Cambridge, Massachusetts is pointing out that they believe the root of every cancerous tumor, is madeup of a handful of aberrant stem cells.
This concept could help explain why tumors can regenerate even after being almost completely destroyed. Furthermore, this could also point medical researchers towards developing new strategies in anticancer drugs and treatments. Effectively, new drugs should be selected based on their lethality to cancer stem cells. Simply shrinking tumors would no longer be seen as effective if these theories prove to be true.
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Posted on February 21, 2006 03:35 PM | Comments (0)
Breast Grown From Stem Cells
The Harvard University Gazette is reporting that stem cell researchers in Australia have developed a complete and functioning breast grown from a single stem cell.
This procedure was done using mouse cells. However, most experts believe it won't be long before it this technology is available for humans.
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Posted on February 9, 2006 10:29 PM | Comments (0)
Lupus Stem Cell Treatment Study in Chicago Shows Promise
News is coming out of Chicago about rebuilding the immune system of patients suffering from Lupus with their own stem cells can promote remission in some of the most severely ill, when other forms of treatment have failed .. this based on a new study out of the US.
Medical researchers at Northwestern Memorial Hospital in Chicago are reporting that they have found that half of the patients treated with stem-cell transplants were disease-free after five years. Addtitionally, the overall survival rate for the patients in the study was 84 per cent.
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Posted on February 2, 2006 12:32 AM | Comments (0)
Breast Cancer Stem Cell Discovery
Some long overdue news .. as I lost a close friend to breast cancer at only 29. It appears that scientists at the Walter and Eliza Hall Institute in Melbourne, Australia have made a break through using stem cella that may help us better understand why some women develop breast cancer and further, suffer recurrences despite undergoing procedures such as chemotherapy.
However, the research team did state that the discovery could lead to specialised individual treatment .. but it would likely be a decade or more before it is publicly available.
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Posted on January 19, 2006 11:53 PM | Comments (0)
Stem Cell Microenvironment Reverses Malignant Melanoma
Chicago - Northwestern University researchers have demonstrated how the microenvironments of two human embryonic stem cell (hESC) lines (federally approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs.
The researchers also showed that these melanoma cells were less invasive following culture on the microenvironments of hESCs.
"Our observations highlight the potential utility of isolating the factors within the hESC microenvironment responsible for influencing tumor cell fate and reversing the cancerous properties of metastatic tumor cells, such as melanoma," said Mary J. C. Hendrix, PhD, professor of pediatrics at the Feinberg School of Medicine, in whose laboratories at Children’s Memorial Research Center the experiments were conducted.
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Posted on December 11, 2005 05:24 PM | Comments (0)
Chemokine Therapeutics Expands Protection of Core Anti-Cancer Technology with Issuance of New U.S. Patent
Vancouver, BC (October 5, 2005) – Chemokine Therapeutics Corp. (the Company) (OTCBB: CHKT; TSX: CTI), a biotechnology company developing chemokine-based therapies to treat cancer, blood disorders, cardiovascular, and infectious diseases, today announced that it has been granted U.S.
Patent No. 6,946,445 relating to a broad range of composition of matter claims, which include claims that cover its lead anti-cancer compound, CTCE-9908, among others. CTCE-9908 is designed to block CXCR4, a receptor found on the surface of cancer cells.
...Posted on October 21, 2005 01:37 PM | Comments (0)
University of Minnesota Researchers Use Stem Cells to Kill Cancer Cells
Stem cell researchers at the University of Minnesota have used human embryonic stem cells to create cancer-killing cells. This latest discovery paves the way for future treatments for various types of cancers. The results of this research is to be published in the October 15 issue of the Journal of Immunology.
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Posted on October 12, 2005 05:48 PM | Comments (0)
A New Link Between Stem Cells and Tumors
Scientists at the European Molecular Biology Laboratory [EMBL] in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Bar de Barcelona [IRB-PCB] in Spain have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in the on-line edition of Nature Genetics [September 4] shows that if key molecules aren't placed in the right locations within stem cells before they divide, the result can be deadly tumors.
Cells in the very early embryo are interchangeable and undergo rapid division. Soon, however, they begin differentiating into more specific types, finally becoming specialized cells like neurons, blood, or muscle. As they differentiate, they should stop dividing and usually become embedded in particular tissues. Some tumor cells are more like stem cells because they are identical, they divide quickly, and in the worst case metastasize they wander through the body and implant themselves in new tissues.
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Posted on September 9, 2005 03:27 PM | Comments (0)
New Stem Cell Mobilizer Improves Cancer Patient Chances For Stem Cell Transplantation
Vancouver, BC, September 6, 2005 - A study published in the current issue of the peer-reviewed journal, Blood, demonstrates that cancer patients who received AMD3100 (MOZOBIl) plus granulocyte-colony stimulating factor (G-CSF) were able to collect more stem cells in less time compared to the standard mobilization regimen, G-CSF alone.
"Cancer patients need better stem cell mobilization, as the strongest predictor of success in transplant is the number of cells available for transplantation", said study lead investigator Dr. Neal Flomenberg, Chief, Division of Medical Oncology, Thomas Jefferson University, Philadelphia, PA.
...Posted on September 8, 2005 01:28 PM | Comments (0)
Additional Stem Cell Articles In This Category
* Biology Professor’s Adult Stem Cell Research Published* Efficacy of High-Dose Chemotherapy with Autologous Stem Cell Supp
* Brain Tumors May Originate With Neural Stem Cells
* The Leukemia & Lymphoma Society Publishes New Coloring Book to He
* Woman "Born Again" following Stem Cell Treatment
* Using Two Different Umbilical Cord Blood Samples To Treat Leukemi
* Chemokine Therapeutics Discusses US Patent for novel cancer drug
* Two New Studies in the British Journal of Haematology Show Potent
* CuraGen Announces Single-Dose Phase I Data on Velafermin (CG53135
* Long-Term Outcomes Studied for Stem Cell Transplant Recipients
* Cloning To Develop Stem Cells In An Effort To Cure Blood Diseases
* U.S. BioDefense To Partner With MD Andersen
* Cellerant Therapeutics Raises $16 Million to Advance Stem Cell-Ba
* Reduced Intensity Allogeneic Stem Cell Transplants Uses for CLL
* Fear of Stem Cells Becoming Cancerous
* Autologous Stem Cell Transplants Improve Progression-Free Surviva
* Mycamine Received FDA Approval - Fujisawa Healthcare, Inc.’s Ec
* Cancer Killing Cells Can Be Produced
* Scientists Identify Switch That Can Turn Stem Cells On and Off
* Protein That Promotes Survival of Stem Cells Might Be Key To Poor
* Plant Derivative FeverFew Attacks Leukemia Stem Cells
* Early Allogeneic Stem Cell Transplants Benefit Acute Myeloid Leuk
* Teva to Commercialize Gamida-Cell's StemEx
* California: Stem Cells Help Achieve Remission in HIV-Associated L
* AnorMED Announces Phase III Trials for AMD3100
* Curis to Co-Develop Cancer Drug with Genentech in the United Stat
* Good Results from Autologous Stem Cell Transplants for HIV Lympho
* Stem Cell Technology could Treat Cancer
* Delirium Can Be Side Effect of Stem Cell Transplant
* Stem Cell Quality Control System Discovered
* Control Mechanism Plays Role in Cellular Proliferation
* Leukemia Genes a Stem Cell Switch
* Michigan Teacher Seeks out Stem Cell Transplant
* Ashland, PA Local Given New Lease on Life with Marrow Stem Cell
* Israeli Gamida-Cell enters Phase III for Leukemia treatment
* Baptist Centers for Cancer Care earns Accreditation for Stem Cell
* Leukemia and Lymphoma Treatments
* Cancer patient in search of a donor
* More Evidence that Leukemia Treatments With Stem Cell Transplants
* Stem Cells' Actual Links to Cancer
* Stem Cell Treatment for Follicular Lymphoma
* 200,000 Chinese ready to save desperate patients
* Stem Cell Leukemia Treatment
* Cord blood treatment gains clout