Spinal / Nervous / Brain Archives
Nerve Cells From Embryonic Stem Cells May Lead To Improved Brain Treatments
According to a study published in The Journal of Neuroscience, scientists at the Burnham Institute for Medical Research have genetically programmed embryonic stem (ES) cells to become nerve cells when transplanted into the brain.
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Posted on June 26, 2008 02:26 PM | Comments (0)
NTF Cells Significant Advantage in Pre-Clinical Study for Parkinson’s Disease
BrainStorm Cell Therapeutics Inc. (OTCBB: BCLI), a leading developer of adult stem cell technologies and therapeutics, announced the results of a pre-clinical study that was conducted with Tel Aviv University between February and May 2008. The study conducted is about signs of impaired motor behavior in a rat model of Parkinson’s improved following transplantation of BrainStorm’s unique Neurotrophic Factor Cells (NTF).
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Posted on June 12, 2008 10:24 AM | Comments (0)
Completion of Proof-of-Principle Studies Demonstrating Efficacy of Cancer Stem Cell Vaccine in Preclinical Model
ImmunoCellular Therapeutics, Ltd. (OTC: IMUC.OB ) (IMUC) a biotechnology company, has announced that recently completed proof-of-principle studies demonstrate efficacy of its cancer stem cell vaccine technology in treating glioblastoma, a form of brain cancer, in preclinical animal models.
The company is planning to submit an Investigational New Drug (IND) application to the FDA later this year to commence a Phase I clinical trial for its cancer stem cell vaccine product, ICT-111, to treat glioblastoma.
...Posted on May 23, 2008 01:54 PM | Comments (0)
Brain Stem Cells To Fight Cancer
Research at Lund University in Sweden provides hope that in the future it may be possible to develop stem cells from the brain into a new way to treat gliomas.
Neural stem cells have been shown to have the ability to recognize signals from tumor cells in the brain and migrate there. If stem cells are injected into a part of the brain in laboratory animals with a glioma in another part of their brain, the stem cells migrate over to the tumor area.
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Posted on January 19, 2007 08:08 AM | Comments (0)
What is Glioblastoma?
Glioblastoma is the most malignant form of brain tumor and has a very poor prognosis.
A glioma is a type of primary central nervous system (CNS) tumor that arises from glial cells. The most common site of involvement of a glioma is the brain, but they can also affect the spinal cord, or any other part of the CNS, such as the optic nerves.
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Posted on January 19, 2007 07:11 AM | Comments (0)
Stem-Cell Transplants to Treat Batten Disease
Oregon Health & Science University's (OHSU) Doernbecher Children's Hospital is getting ready to start a phase I trial to test the safety of stem cell transplants to treat Batten disease, and not necessarily whether it works.
In this trial, six children with symptoms of the disease will be given transplants of stem cells at two different doses and followed for a year.
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Posted on October 17, 2006 11:18 PM | Comments (0)
Using Stem Cells as Drug Delivery To Bypass Blood Brain Barrier
The blood brain barrier is a well known problem to neurologists trying to introduce certain compounds to the brains of patients suffering from things like Parkinson's and Alzheimer's. However, a new method using stem cells may be a solution.
One stem cell researcher at the University of Wisconsin-Madison is working on engineering and then implanting progenitor brain cells which have been derived from stem cells to deliver growth factors that show proven clinical benefits for Parkinson's disease.
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Posted on March 31, 2006 01:43 PM | Comments (0)
Stem Cell Researchers Again Improving Spinal Cord Injured Rats
Stem cell researchers are once again looking into the brains of mice and how some stem cell therapies can help restore walking ability in laboratory rats with spinal-cord damage. Canadian stem cell researchers are now digging into spinal stem cell therapy for treating spinal damage.
This new study has stem cell researchers looking at neural precursor cells, where is a type of stem cell that has begun differentiating into a central nervous system cells. Specifically, these cells are derived from mouse brains.
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Posted on March 29, 2006 11:10 AM | Comments (0)
Samaritan Pharmaceuticals Announces Alzheimer Stem Cell Treatment
A new Alzheimer adult stem cell drug called SP-sc04 has being announced by stem cell research firm, Samaritan Pharmaceuticals Inc. (AMEX:LIV).
The goal of this new drug is to trigger normally dormant brain neuronal stem cells to differentiate into adult neuron cells.
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Posted on March 21, 2006 11:42 PM | Comments (0)
Bone Marrow Derived Stem Cells Investigated For Stroke Therapy
Stem cell researchers in Japan investigating bone marrow stromal cells may have discoverd how to restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders.
"Our study showed that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke, improving their neurological symptoms," said Satoshi Kuroda, M.D., Ph.D., who is with the department of neurosurgery at Hokkaido University School of Medicine in Sapporo, Japan. "How the transplanted bone marrow stromal cells restore the lost neurologic function is not clear," added the co-author of "Improved Expression of a-Aminobutyric Acid Receptor in Mice With Cerebral Infarct and Transplanted Bone Marrow Stromal Cells: An Autoradiographic and Histologic Analysis."
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Posted on March 17, 2006 01:28 PM | Comments (0)
Multiple Sclerosis Sufferer Sees Results From Stem Cell Therapy
A new stem cell procedure designed to treat Multiple Sclerosis has been tested in Canada with some significant results for at least one person so far.
Doctors harvested stem cells from Jennifer Molson of Ottawa. Following that, Molson was given high doses of chemotherapy was then used to to wipe out her immune system. After a period of recovery, the doctors then reinjected Molson's her own stem cells back into her.
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Posted on March 17, 2006 01:13 PM | Comments (0)
Stroke Stem Cell Therapy Shows Promise
Stem Cell Therapeutics Corp. (SSS.V) os reporting results from its Phase I pharmacokinetic clinical trial for therapeutic treatment targeting strokes. The drug regimen, NTx-265, consists of two drugs that trigger neural stem cell proliferation.
The study evaluated evidence that these two neural stem cell proliferation inducing drugs did in fact reach the cerebrospinal fluid when administered to human subjects with an intact blood-brain barrier.
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Posted on March 17, 2006 12:54 PM | Comments (0)
Clinical Stem Cell Trial in Oregon To Treat Pediatric Neurodegenerative Disorder
Another clinical trial is being held which further helps bring stem cell research out of the lab and to patients. This time the stem cell trial is in Oregon and will be investigating the safety of injecting human stem cells directly into patient's brains with the hope to treat pediatric neurodegenerative disorder.
Theis latest trial being held at Doernbecher Children's Hospital at Oregon Health & Science University is to study HuCNS-SC.
HuCNS-SC is a new central nervous stem cell product developed by StemCells, Inc. of Palo Alto, Calif. The goal is to see if this new product can slow the progression of two forms of Batten disease.
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Posted on March 13, 2006 02:20 PM | Comments (0)
Spinal Regeneration Stem Cell Therapy Studied at Univ. of Louisville
News regarding spinal and nervous system stem cell research has been thin lately. However, hopefully we will get more along these lines that will allow us to see what progress is being made.
The last news we posted related to this was regarding Hans Keirstead of University of California-Irvine making paralyzed rats walk again.
This time through, this is news coming out of the University of Louisville, Kentucky that may also lead to future treatments for spinal cord injuries .. as well as multiple sclerosis (MS), and Parkinson's disease.
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Posted on March 10, 2006 01:38 AM | Comments (0)
Stem Cell Research at Cedars-Sinai Showing Protection Against Brain Tumors
This is a quicky .. and will look for more info on this .. but news is 'sneaking' out that researchers at Cedars-Sinai Medical Center’s Maxine Dunitz Neurosurgical Institute have discovered a new cytokine thats linked to neural stem cells derived from bone marrow.
Using this, the researchers are working to perfect a tool to track and kill malignant brain tumor cells and further, provide long-term protection to prevent the tumor from returning.
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Posted on March 2, 2006 01:10 AM | Comments (0)
Stem Cell Therapy To Treat Huntington's Disease
It is going to soon be very difficult to track all the different stem cell therapy studies out there. So many different diseases and conditions are being evaluated for treatement using stem cells.
The latest case in point, news of a new study is going to come out in this month's Lancet Neurology journal. This latest news regards stem cell transplants in treating Huntington's disease.
Researchers are evaluating the benefits of an experimental stem cell therapy in reducing the most common symptoms Huntington's like muscle stiffness and memory loss. However, based on the current results, the benefits peaked after two years and then faded four to six years after the procedure.
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Posted on February 27, 2006 11:34 PM | Comments (0)
Pre-clinical Data From ReNeuron With ReN004 Human Stem Cell Lines For Parkinson's Disease
ReNeuron Group plc has announced that initial testing of its candidate stem cell lines, ReN004, proved to have attributes that may help fixing the neurological deficits seen in Parkinson's disease.
C-mycERTAM stem cell expansion technology was used to generate the human cell lines, which were pre-screened for both genetic stability and their ability to differentiate into tyrosine hydroxylase (TH)- a marker for a dopaminergic stem cell phenotype.
...Posted on February 23, 2006 11:55 AM | Comments (0)
Future Medical Technologies May Identify the Early Onset of Alzheimer's and Enable Stem Cell Therapy
Molecular Imaging Advancements Simultaneously Locate, Diagnose and Treat Disease
CHICAGO, Nov. 29, 2005 – Siemens Medical Solutions today revealed its vision for a new world of medicine where doctors can predict and prevent disease before symptoms appear. By identifying and tracking disease-related events in the body’s cells, Siemens envisions that, among other applications, molecular medicine will have a tremendous impact on the detection of Alzheimer’s disease, and the effectiveness of stem cell therapy.
...Posted on December 11, 2005 06:01 PM | Comments (0)
StemCells, Inc. Receives Clearance to Initiate Phase I Clinical Trial of Neural Stem Cells to Treat Batten Disease
First-Ever FDA-Approved Trial to Transplant Human Neural Stem Cells
PALO ALTO, Calif., (October 20, 2005) – StemCells, Inc. (NASDAQ: STEM) today announced that it has received clearance from the U.S. Food and Drug Administration (FDA) to begin a Phase I safety and preliminary efficacy trial of the Company’s proprietary human neural stem cell product ─HuCNS-SC ™─ to treat Batten disease. Batten disease is a rare, fatal genetic disorder that affects the central nervous system of children. This is the first-ever FDA-approved clinical trial to use a purified composition of human neural stem cells as a potential therapeutic agent in humans.
...Posted on November 4, 2005 01:17 PM | Comments (0)
Adult Stem Cells Aid Recovery In Animal Model Of Cerebral Palsy
Researchers report that a recent study, run at Medical College of Georgia, shows the adult stem cell therapy quickly and significantly improving the recovery of motor function in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy.
Co-authors on the study include Dr. David Hess, chair of the MCG Department of Neurology; Dr. Lin Xu, research scientist; Drs. Noriyuki Matsaukawa, Guolong Yu, Takao Yasuhara and Koichi Hara, postdoctoral fellows; and Athersys scientists Robert Mays, Jim Kovach and Robert Deans.
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Posted on October 21, 2005 06:43 PM | Comments (0)
Additional Stem Cell Articles In This Category
* Markers Of Brain Cell Development May Help Success Of Stem Cell T* UCSF Team Advances Probe Of Neural Stem Cell-Brain Tumor Link
* Restorative Therapies, Inc., Receives FDA Clearance for RT300-S
* South Korean Scientists Find Mechanism for Neural Stem Cell Death
* Efficacy of High-Dose Chemotherapy with Autologous Stem Cell Supp
* Stem Cell Sciences To Commercialise Breakthrough Neural Stem Cell
* Paralyzed Michigan Teen Feeling Good After Stem Cell Therapy In P
* Gradient Guides Nerve Growth Down Spinal Cord
* Stem Cells Provide Greater Understanding of Neurological Diseases
* Brain Tumors May Originate With Neural Stem Cells
* More Spinal Stem Cell Therapy News For Treating Spine Damage
* Swedish Researchers Create New Brain Cells From Stem Cells
* Combination Therapy Leads to Partial Recovery from Spinal Cord In
* Genetically Engineered Stem Cells Healing Rats Spines?
* USC Partnership Studies Stem Cells In Quest To Restore Nervous Sy
* The Debate Over Testing Human Brain Cells in Primates
* Stem Cells Involved In Protecting Brain and Nervous System
* Stem Cells Implanted in Brain in Sufferer a Cerebral Infarction
* PharmaFrontiers Announces Positive Interim Results of Two Phase I
* Researchers Look at Stem Cells to Repair Damage Caused by Multipl
* Gene Keeps Neural Cells on Correct Developmental Path
* Unrestrained Retina Too Much of A Good Thing
* Company Profile for StemCell Pharma, Inc.
* Following Up On A Paralyzed Stem Cell Transplant Recipient
* Wired On Stem Cells and Paralysis Recovery In Rats
* Reeve-Irvine Research Center's Press Release On Stem Cell Treatm
* More News On Stem Cells and Spinal Cord Injury Repair
* Geron Announces Publication of Studies Showing Oligodendrocyte Pr
* Stem Cells From The Brain To Possibly Cure Diabetes
* Human Neural Stem Cells Persist and Influence Nerve Cells in Rat
* University of Wisconsin Stem Cell Research Targeting ALS
* 2nd Stem Cell Operation Planned for Patient Hwang
* A Paralyzed Patient's Perspective on Stem Cell Treatment In China
* Samaritan Updates Alzheimer's and HIV Drug Development
* StemCells, Inc. Issues FDA Update on Proposed Clinical Trial
* Brainstorm Cell Therapeutics Developing Parkinson's Treatment
* Stem Cells Into Brain Cells?
* Willie Terpstra Able To Speak Following Stem Cell Treatment
* Promising Line of Human Embryonic Stem Cells for Parkinson's Dise
* New Zealander Willie Terpstra Awaits Word on Timing of Stem-Cell
* Stem Cell Based Drug Enters Commercial Testing In Korea
* Michael J. Fox to Address Reform Jewish Movement's Consultation o
* Mouse Will Have 100% Human Brain Cells
* Quadriplegic hopes surgery in Portugal can cure his paralysis
* Fernandes Approved for Stem Cell Surgery in Portugal
* Latest Stem Cell News From Johns Hopkins
* Ian Wilmut (Creator of Dolly) Plans to Obtain Stem Cells for Lou
* Sweden: Stem Cell Therapy for Spinal Injury
* Florida: New Stem Cell Research Targetting Alzheimer’s
* More on UK Team Researching Parkinson's Treatment
* Stem Cells Coaxed Into Becoming Motor Neurons
* Michael J. Fox Foundation for Parkinson's Research Announced $1 M
* Researchers in Russia Investigating Spinal Cord Treatment
* Paraplegic Improving After Stem-Cell Implant
* More on the Latest Stem Cell Work In Lisbon
* Medical Facility To Implant Stem Cells to Treat Spinal Injury
* Parkinson's Symptoms in Monkeys Reversed with Stem Cell Treatment
* Stem Cell Researcher Makes Paralyzed Rats Walk
* Stem Cell Treatment Effective in Treating Cerebral Infarction
* Russian scientists treating spinal cord damage with non-embryonic
* Stem cells may heal multiple sclerosis damage
* New Research Could Improve Safety of Stem Cell Transplants
* Stem Cells may actually fuel brain cancer
* Embryonic Stem Cells targetting Spinal Cord Repair