May 2008 Archives
Bone Repair Using Patient's Stem Cells
Researchers at the University of Twente, The Netherlands, have just shown that if the enzyme PKA is previously activated in the stem cells in the lab, following implantation, results in substantial bone formation.
This opens up new ways of repairing bone tissue using cell material from the patient.
Enzyme induces adult stem cells to grow bone, but now it has been difficult to induce adult human stem cells to produce bone, e.g. in order to repair bone tissue.
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Posted on May 27, 2008 12:09 PM | Comments (0)
Completion of Proof-of-Principle Studies Demonstrating Efficacy of Cancer Stem Cell Vaccine in Preclinical Model
ImmunoCellular Therapeutics, Ltd. (OTC: IMUC.OB ) (IMUC) a biotechnology company, has announced that recently completed proof-of-principle studies demonstrate efficacy of its cancer stem cell vaccine technology in treating glioblastoma, a form of brain cancer, in preclinical animal models.
The company is planning to submit an Investigational New Drug (IND) application to the FDA later this year to commence a Phase I clinical trial for its cancer stem cell vaccine product, ICT-111, to treat glioblastoma.
...Posted on May 23, 2008 01:54 PM | Comments (0)
Bone Cells that Influence Blood Stem Cell Replication and Migration
Osteoblasts, cells responsible for bone formation, have been found by researchers at the Joslin Diabetes Center to be directly involved in the proliferation and expansion of blood-forming hematopoietic stem cells.
The finding improves understanding of how such stem cells work and could have implications for the future of bone marrow and peripheral blood progenitor cell transplants, which are used in the treatment of a variety of illnesses – including leukemia, lymphoma and immunodeficiency.
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Posted on May 22, 2008 02:50 PM | Comments (0)