Faster and More Efficient Cell Harvest From Pall Technology
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The Pall Corporation Filter Harvest System was found to have the potential to become a valuable tool to help realize the promise of regenerative medicine. Filter Harvest System is a transformative filtration-based technology for the isolation and enrichment of cells, more efficient and faster than traditional technology used for cell separation.
Lisa Bradbury, Ph.D., Director, R&D Cell Therapy, Pall Life Sciences, presented data comparing the Pall Filter Harvest System to a traditional open-system, density gradient, centrifuge-based method for isolation of mononuclear cells (MNC) from whole blood. The system was found to:
- significantly reduce processing time;
- it can be performed in less than 15 minutes compared to an average processing time of about 2.5 to 4 hours with the Ficoll gradient technique;
- it has also exhibited higher yield of MNCs for significantly better recovery (60% to 95%) than the Ficoll method.
The Pall Filter Harvest System can be used as a closed system that adheres to Good Manufacturing Practice (cGMP), furthering the ability to comply with increasingly stringent regulations for safe, reproducible and efficacious cell products.
The Pall system can be used to harvest cells from a broad range of biological samples including peripheral blood, bone marrow and umbilical cord blood.
Posted on May 16, 2006 01:02 PM