Bone Marrow Derived Stem Cells Investigated For Stroke Therapy
Related News: Spinal / Nervous / BrainStem cell researchers in Japan investigating bone marrow stromal cells may have discoverd how to restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders.
"Our study showed that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke, improving their neurological symptoms," said Satoshi Kuroda, M.D., Ph.D., who is with the department of neurosurgery at Hokkaido University School of Medicine in Sapporo, Japan. "How the transplanted bone marrow stromal cells restore the lost neurologic function is not clear," added the co-author of "Improved Expression of a-Aminobutyric Acid Receptor in Mice With Cerebral Infarct and Transplanted Bone Marrow Stromal Cells: An Autoradiographic and Histologic Analysis."
Thusfar, researchers hope that that cells found in an adult’s bone marrow (stromal stem cells) may provide a safe source for replacing brain cells lost to neurological diseases like Alzheimer’s and Parkinson’s.
Studies around the world has indicated that stem cells taken from adult human bone marrow may differentiate into neural cells that could then possibly be transplanted into the brain.
This study's findings demonstrated that bone marrow stromal cells "may contribute to neural tissue regeneration by migrating toward the periinfarct area and acquiring the neuron-specific receptor function," reports the Journal of Nuclear Medicine.
Uncovering How Bone Marrow Stromal Cells Can Potentially Regenerate Brain Tissue
Posted on March 17, 2006 01:28 PM