What Is the Hedgehog Signaling Pathway?
Related News: Stem Cell DefinitionsThe Hedgehog Signaling Pathway is a mechanism within the body to control the normal development and growth of stem cells and certain tissues systems.
The Hedgehog gene got its name after studies of fruit flies lacking it revealed that cell types were jumbled, instead of organized in the neat lines of normal flies. The jumbled cells, the scientists decided, resembled the round, porcupine-like animal.
It is also known, humorously, as Sonic The Hedgehog Signaling Pathway ...
Studies have shown that there is a link to abnormal expression of Hedgehog pathway signaling and the development of certain forms of cancer, including basal cell carcinoma, small cell lung cancer, medulloblastoma, pancreatic cancer, and others cancers.
Some relevant links:
A Very good diagram showing how the Hedgehog Signalling Pathway works ...
Posted on August 10, 2005 05:47 PM