The stem cell therapy drugs have been shown, in cells cultures and in animal, to awaken brain dormant stem cells and to transform them (differentiate) into new neurons. The Alzheimer's diagnostic is a simple blood test that has proven superior to the invasive spinal taps and MRIs currently used. Finally, the Alzheimer's animal model offers a model to rapidly screen and develop innovative drugs for Alzheimer's disease.

Alzheimer's Stem Cell Drugs

Samaritan is fast tracking its development of its neuronal stem cell therapy drugs (SP-sc4 and SP-sc7) that can induce dormant brain neuronal stem cells to differentiate rapidly into adult neuron cells as a novel treatment for Alzheimer's disease and other neurodegenerative disorders. Repairing brain damage by replacing the lost neurons and restoring neuronal function is certainly the most ambitious and exciting challenge physicians and scientists are currently facing. In that aspect, the concept of stem cell therapy is extremely promising. Hence, the access to the differentiation of stem cells into neurons may serve as a database of specialized cells for regenerative medicine as a treatment for neurodegenerative diseases and brain stroke.

SP-sc4 and SP-sc7 Development

Screening a database/collection of naturally occurring compounds, identified compounds that were efficacious, in inducing "in vitro" and in rats' "in vivo" neural stem cell differentiation, and neurogenesis. Further, "in vivo" studies in animal models of neurodegenerative disease are in progress, in order to validate the use of these compounds in regenerating the neuronal network from pre-existing stem cells in the adult.

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