Stem Cell Quality Control System Discovered
Related News: Stem Cells and CancerResearchers at the University of California, San Diego, have discovered that embryonic stem cells have a mechanism that allows them to divide indefinitely while avoiding the duplication of genetically damaged cells that can lead to cancer.... Read On
The researchers found that p53 activated by DNA damage in mouse embryonic stem cells directly suppresses the expression of a gene called Nanog that is necessary for stem cell self-renewal. Suppressing Nanog causes embryonic stem cells to differentiate into other cell types.
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Posted on December 30, 2004 12:25 PM