Stem Cells Could Reverse Cirrhosis of the Liver
Related News: Stem Cells and LiverLondon's Hammersmith Hospitals team in a test, will use a patient's own bone marrow stem cells to treat Cirrhosis. New Scientist magazine also reports on a Japanese team looking at using the treatment for liver fibrosis....This is a massive step towards moving away from liver transplants ... which are touchy at best.... Read On
Currently, the only hope for many patients has been a liver transplant - but there are too few organs available, so other treatments are urgently needed.
The UK research involves taking blood from the patient and separating it into its component parts.
Stem cells are isolated from the white blood cells and injected into the hepatic artery in the liver, while the red blood cells are returned to the body through the arm.
Laboratory tests have shown the treatment can improve the function of the liver by repopulating it with stem cells.
In the Japanese study, mouse livers were damaged by injecting them with a chemical which causes fibrosis, where scar tissue develops in the liver.
It can go on to develop into cirrhosis when nodules of cells form at the junctions of the fibrous strands.
After four weeks, they took bone marrow cells from donor mice that had had been treated with a jellyfish gene to make their cells glow green.
This allowed the researchers to track the progress of the cells.
Posted on December 21, 2004 12:13 PM