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Nerve Cells From Embryonic Stem Cells May Lead To Improved Brain Treatments

Related Entries: Spinal / Nervous / Brain

According to a study published in The Journal of Neuroscience, scientists at the Burnham Institute for Medical Research have genetically programmed embryonic stem (ES) cells to become nerve cells when transplanted into the brain.

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June 26, 2008 02:26 PM

Molecular Imaging Used To Track Stem Cells In Tumors

Related Entries: Stem Cells and Cancer

Researchers at Society of Nuclear Medicine's 55th Annual Meeting, June 14-18, say that new therapies offer promise for patients

Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms, according to researchers at SNM's 55th Annual Meeting. This ability could lead to major advances in the use of stem cell therapies to treat cancer.

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June 16, 2008 06:15 PM

NTF Cells Significant Advantage in Pre-Clinical Study for Parkinson’s Disease

Related Entries: Spinal / Nervous / Brain


BrainStorm Cell Therapeutics Inc. (OTCBB: BCLI)
, a leading developer of adult stem cell technologies and therapeutics, announced the results of a pre-clinical study that was conducted with Tel Aviv University between February and May 2008. The study conducted is about signs of impaired motor behavior in a rat model of Parkinson’s improved following transplantation of BrainStorm’s unique Neurotrophic Factor Cells (NTF).

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June 12, 2008 10:24 AM

Bone Repair Using Patient's Stem Cells

Related Entries: Bone and Cartilage

Researchers at the University of Twente, The Netherlands, have just shown that if the enzyme PKA is previously activated in the stem cells in the lab, following implantation, results in substantial bone formation.

This opens up new ways of repairing bone tissue using cell material from the patient.

Enzyme induces adult stem cells to grow bone, but now it has been difficult to induce adult human stem cells to produce bone, e.g. in order to repair bone tissue.

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May 27, 2008 12:09 PM

Completion of Proof-of-Principle Studies Demonstrating Efficacy of Cancer Stem Cell Vaccine in Preclinical Model

Related Entries: Spinal / Nervous / Brain, Stem Cell Research

ImmunoCellular Therapeutics, Ltd. (OTC: IMUC.OB ) (IMUC) a biotechnology company, has announced that recently completed proof-of-principle studies demonstrate efficacy of its cancer stem cell vaccine technology in treating glioblastoma, a form of brain cancer, in preclinical animal models.

The company is planning to submit an Investigational New Drug (IND) application to the FDA later this year to commence a Phase I clinical trial for its cancer stem cell vaccine product, ICT-111, to treat glioblastoma.

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May 23, 2008 01:54 PM

Bone Cells that Influence Blood Stem Cell Replication and Migration

Related Entries: Stem Cell Research

Osteoblasts, cells responsible for bone formation, have been found by researchers at the Joslin Diabetes Center to be directly involved in the proliferation and expansion of blood-forming hematopoietic stem cells.

The finding improves understanding of how such stem cells work and could have implications for the future of bone marrow and peripheral blood progenitor cell transplants, which are used in the treatment of a variety of illnesses – including leukemia, lymphoma and immunodeficiency.

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May 22, 2008 02:50 PM

Boston University Successfully Treats Amyloidosis Patients Using A Stem Cell Procedure

Related Entries: Stem Cell Research

Researchers at Boston University Medical Center (BUMC), Stem Cell Transplant Program and the Amyloid Treatment and Research Program, have found that tandem cycles of high-dose chemotherapy and blood stem cell transplantation can help treat patients with immunoglobulin-light chain (AL) Amyloidosis who did not respond to initial treatment with this method.

These findings were published on-line in the June 25th issue of Bone Marrow Transplantation.

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July 6, 2007 02:31 PM

What Is Amyloidosis?

Related Entries: Stem Cell Definitions

Amyloidosis is a group of diseases in which one or more organ systems in the body accumulate deposits of abnormal proteins.

The name "amyloidosis" was first used more than 100 years ago but cases were described over 300 years ago. However, only within the past 20 years have physicians understood the specific make-up and structure of amyloid protein.

Although amyloidosis is not cancer, it is very serious. It may be disabling or life threatening. However, growing awareness of the condition seems to be leading to substantial new research and treatment alternatives.

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July 6, 2007 02:17 PM

Muscle Stem Cells An Option To Treat Congestive Heart Failure

Related Entries: Heart / Cardio News

As a new wave of stem cell research continues, cardiologists are trying to tap into the self-renewing cells' life-saving potential.

Scientists have performed the first U.S. controlled, randomized Phase I clinical trial using a three-dimensional guided catheter system to deliver muscular stem cells to the heart.

The study was presented at the American College of Cardiology's Innovation in Intervention: i2 Summit in New Orleans, La.

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March 26, 2007 05:16 PM

Adult Stem Cells Decide the Fate of Their Daughters

Related Entries: Stem Cell Research

According to new studies by researchers at the Howard Hughes Medical Institute (HHMI)the intestinal stem cells make important decisions about their fate by communicating directly with their daughter cells, instructing them to become one of two possible cell types.

The studies bring researchers a bit closer to understanding how adult stem cells decide to make the cell type that best meets the current needs of the organism.

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February 16, 2007 02:38 PM

 
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